Genetics And Mental Illnesses Essay Research Paper

Geneticss And Mental Illnesses Essay, Research Paper

Discoveries in genetic sciences have helped alter the manner society looks at mental unwellnesss such as frenzied depression and schizophrenic disorder. A coevals ago, the taking theory about schizophrenic disorder was that this annihilating emotional and mental upset was caused by cold and distant mothering, itself the consequence of the female parent & # 8217 ; s unconscious want that her kid had ne’er been born. A nation-wide lobbying attempt was launched to battle such baseless female parent blaming, and 20 old ages subsequently that artefact of the Freudian epoch is wholly discredited. It & # 8217 ; s widely accepted today that psychotic upsets are encephalon upsets, likely with familial roots ( Herbert 72 ) .

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Merely like every other subject in the genetic sciences arguments there are a few sides to the argument on the causes of mental upsets. One side feels mental unwellnesss are caused strictly by familial heritage and another feels they are caused by environmental factors. A different side feels that it is a combination of the two.

The job is that most people take a side that supports either genetic sciences or environment when most instances are non merely familial, but besides environment. Take this state of affairs for illustration. I have a 13 twelvemonth old friend who has been depressed a batch for the past few months, possibly even a twelvemonth. Her female parent late decided to acquire her screened for depression. Well, they decided that she has a & # 8220 ; chemical instability & # 8221 ; in her encephalon that causes her to be depressed. In other words, she & # 8217 ; s depressed because genetically she & # 8217 ; s unnatural and that abnormalcy keeps her encephalon from doing a certain chemical she needs to maintain from being depressed. The thing is that & # 8217 ; s non the lone ground she & # 8217 ; s depressed. She & # 8217 ; s non really happy at place. Her parents won & # 8217 ; t allow her make anything, which includes seeing her friends outside of school most of the clip. They made her work all summer in her stepfather & # 8217 ; s store and about didn & # 8217 ; t allow her discontinue when school started. She & # 8217 ; s merely allowed one phone call a twenty-four hours and it is limited to five to ten proceedingss.

Now, every bit far as I am concerned, that is ground to be depressed. With fortunes like this, possibly her depression International Relations and Security Network & # 8217 ; t all merely the chemical instability caused by her cistrons, and possibly it has something to make with her environment. This state of affairs illustrates the thought that mental unwellnesss are non merely familial, but are besides environmentally caused. As Leonard Darwin says in & # 8220 ; The Need for Eugenic Reform & # 8221 ; , & # 8220 ; In analyzing instances of insanity both factors must ever be taken into history, and the lone logical class to follow is to wholly fling all such phrases as due to heredity and due to environment. & # 8221 ;

This does non intend that genetic sciences does non sometimes do the depression. For illustration, David Rosenthal summarized tonss of surveies describing that schizophrenic disorder, a mental unwellness, bunchs in households ; that is, relations of a schizophrenic are well more likely to go schizophrenic than are people without schizophrenic relations & # 8221 ; ( Stark 134 ) . David G. Myers says at one point, & # 8220 ; Some people more than others seem genetically predisposed to peculiar frights and high anxiousness. Identical twins frequently develop similar phobic disorder, in some instances even when raised individually & # 8221 ; ( Myers 464 ) .

Many surveies have been done on the topic of twins who develop the same mental unwellnesss. In one survey it was found that & # 8220 ; one brace of 35-year old indistinguishable female twins independently developed claustrophobia & # 8221 ; ( Myers 464 ) . Old ages of surveies of households, adopted kids, and twins separated at birth, suggest that both schizophrenic disorder and manic-depressive unwellness tally in households & # 8221 ; ( Herbert 77 ) . These jobs become more outstanding in cases where the stricken individual is an indistinguishable twin ( Myers 464 ) . This means that the closer you are genetically, the more likely you are to be schizophrenic besides. The hazard of holding the cistron is 10-15 % if you have an affected sibling, but merely 2-3 % if your parent is the stricken relation ( Wilson ) . It has been proven that & # 8220 ; the 1-in-100 odds of any individual & # 8217 ; s being diagnosed with schizophrenic disorder become 1 in 10 among those with an stricken sibling or parent, and near to 1 in 2 among those who have an afflicted twin ( Myers 478 ) . This is true & # 8220 ; whether the twins are reared together or apart & # 8221 ; ( Myers 478 ) . Thus it is obvious that genetic sciences must play some portion in the causation of some mental upsets.

A survey of an Amish community was undertaken by Medical Sociologist Janice Egeland. & # 8220 ; In this community of quiet-spoken low pacificists, such behaviour stands out against the societal landscape & # 8221 ; ( Wallis 67 ) . The study that was published in Nature confirmed the nexus between frenzied depression and the & # 8220 ; human chromosome 11. & # 8221 ; & # 8220 ; & # 8216 ; This is the first presentation of a possible familial footing for one of the major mental upsets, & # 8217 ; says Dr. Darrel Regier, manager of the division of clinical research at the National Institute of Mental Health ( NIMH ) . & # 8216 ; The survey Usshers in a new epoch of psychiatric research & # 8217 ; & # 8221 ; ( Wallis 67 ) . Unfortunately these recent finds do nil to do diagnosing specific plenty in familial guidance. In other words, it is still non possible to find whether or non a individual will decidedly hold the mental unwellness ( Wilson ) .

Many people feel about mental unwellnesss being caused by genetic sciences the manner they did when Christopher Columbus foremost ca

me up with the thought that the universe was round. In other words they feel the old manner of looking at mental unwellnesss, which is that they are caused by the environment of the individual is the right reply and all other replies are nonsensical. “‘The major job [ in this research country ] is all the non-replications, ’ says Elliot Gershon of the National Institute of Mental Health ( NIMH ) in Bethesda, Maryland. ‘The inquiry is why? ’” ( Barnes 314 ) . What he means is that even though two people have the same environment and one becomes schizophrenic, excessively frequently the other individual doesn’t. This makes it difficult to turn out that mental unwellnesss are wholly environmental. If mental unwellnesss were strictly environmental wouldn’t everyone who lives in the same type of environment have schizophrenia? This shows the inability to turn out environmental causes of mental unwellnesss so far.

Many anti-genetic cause trusters feel the non-replications are because genetic sciences do non hold anything to make with the causes of mental unwellnesss. Miron Baron, of Columbia University College of Physicians says, & # 8220 ; There are now a figure of surveies in the literature [ including his ] that have reported linkage on the X chromosome in major depressive unwellness and a figure of other surveies that have reported something different & # 8221 ; ( Barnes 313 ) . This shows that even though it is believed to be strictly familial or strictly environmental, surveies have shown that this is non possible. The consequences differ from survey to analyze. One shows it is pure genetic sciences and the other shows it is pure environment. This proves it is neither genetic sciences nor environment entirely, but both of them together. Later in the article the writer quotes Kenneth Kidd of Yale University School of Medicine about methodological analysis. He says, & # 8220 ; & # 8216 ; A linkage analysis can non be done without stipulating a manner of heritage, without stipulating that a individual cistron causes the disease, without stipulating how penetrant the cistron is & # 8217 ; & # 8221 ; ( Barnes 314 ) . What this means is that in order to turn out it genetically caused, they would hold to insulate a individual cistron that is found in all patients that causes the mental unwellnesss. This information is still non known for diseases such as schizophrenic disorder and frenzied depression, so how can it be proved that genetic sciences has anything to make with mental unwellnesss? James Gusella of Massachusetts General Hospital in Boston says this about the information needed, & # 8220 ; The lone manner to turn out heterogeneousness is to place or insulate all the different cistrons. And this would be enormously hard with current attacks & # 8221 ; ( Barnes 314 ) . The really people who are supporting familial links to mental unwellnesss are forced to state that it can non yet be proved. As for the experiment done with the Amish, Claudia Wallis says this in her article, Is Mental Illness Inherited? , & # 8220 ; Does the same familial defect drama function in all frenzied depression? Not needfully & # 8221 ; ( p.67 ) .

There is no cogent evidence that mental unwellnesss are caused by one job entirely. & # 8220 ; Behavioral geneticists suspect that several cistrons may underlie the unwellness, and that some environmental stress-perhaps a virus or birth complications-also might be required to trip the upset & # 8221 ; ( Herbert 77 ) . & # 8220 ; The disagreements could ensue from any of several factors, he suggests. One for case, is familial heterogeneousness, intending that the same group of upsets has different familial causes. Another is misdiagnosis of certain people in the households under survey, & # 8221 ; says Miron Baron ( Barnes 313 ) . What this means is that mental unwellnesss are non caused by either genetic sciences or environment entirely. They are the consequence of many combinations of both. As stated in The Need for Eugenic Reform by Leonard Darwin, & # 8220 ; If either heredity or environment is ignored, when sing the jobs here dealt with, many booby traps will be found in our way from which flight is hard for those who have been therefore entrapped & # 8221 ; ( 229 ) .

Equally far as I & # 8217 ; m concerned neither genetic sciences nor environment have sole consequence over mental unwellnesss. While some mental unwellnesss may be caused merely by genetic sciences or merely by environment, others are caused by both. & # 8220 ; Not merely do two brothers who develop schizophrenic disorders have a similar familial heritage, they besides grew up in the same place with the same parents and were exposed to similar societal fortunes outside the place & # 8221 ; ( Stark 134 ) . As we continue to larn more about our familial make-up we will larn that the mental illnesses we now believe to be caused merely by environment or merely by genetic sciences, are truly caused by a combination of both.

Barnes, Deborah M. & # 8220 ; Trouble in Gene Linkage Land & # 8221 ; . Science.

1989, v243 n4889, Jan 20, pgs.313-314.

Darwin, Leonard. The Need for Eugenic Reform. Garland

Publishing, Inc. : New York. 1984. pgs. 227-238.

Herbert, Wray. & # 8220 ; Politicss of Biology & # 8221 ; . U.S. News and World

Report. April 21, 1997, pgs.72-80.

Myers, David G. Psychology. Deserving Publishers: Holland,

Michigan 1998. pgs.454-455, 464, 478-479.

Stark, Rodney. Sociology. Wadsworth Publishing Co. :

Belmont 1996. pg.134.

Wallis, Claudia. & # 8220 ; Is Mental Illness Inherited? & # 8221 ; . Time.

1987, v129 n10, March 9, pg.67.

Wilson, Wendy. & # 8220 ; New Light Continues to be Thrown on

Inherited Schizophrenia & # 8221 ; . The Medical Post. April 2, 1996-gotten off the LINK